Research directions

• Population genetic, molecular phylogenetic studies of rare endemic and relict species of Kazakhstan;
• Creation of an in vitro biobank of rare, endemic and medicinal plant species;
• Study of molecular genetic mechanisms of plant adaptation to environmental stress factors;
• Development of biotechnologies for creating economically valuable forms of plants;
• Development of computer programs and genetic databases.

Innovative developments

• A technology has been developed for microclonal propagation of the valuable medicinal plant Rhodiola rosea The developed technology makes it possible to obtain own-rooted Rhodiola rosea plants with a closed root system (CRS) for plantation cultivation in order to obtain medicinal raw materials;
• Technologies have been developed for long-term storage in vitro culture of rare medicinal and endemic plants Rhodiola, Allium sp., Paeonia anomala, Rhaponticum carthamoides;
• Technologies for genetic certification of wheat varieties and breeding lines using various types of markers have been developed.

Provision of services

• Accelerated propagation of rare, endemic and medicinal plants;
• Molecular genetic certification of plant varieties and lines;
• DNA barcoding of plants and phytopathogenic microorganisms;
• Phytoexamination of seed and planting material.

Core publications

Terletskaya, N., Turzhanova, A., Khapilina, O., Zhumagul, M., Meduntseva, N., Kudrina, N., Korbozova, N., Kubentayev, S., & Kalendar, R. (2023)
Genetic diversity in natural populations of Rhodiola species of different adaptation strategies. Genes, 14(4), [794]. https://doi.org/10.3390/genes14040794

Khapilina O, Turzhanova A, Danilova A, Tumenbayeva A, Shevtsov V, Kotukhov Y, Kalendar R 2021.
Primer Binding Site (PBS) profiling of genetic diversity of natural populations of endemic species Аllium ledebourianum Schult.. BioTech, 10(4): 23. DOI:10.3390/biotech10040023 https://www.scimagojr.com/journalsearch.php?q=21100826384&tip=sid&clean=0

Khapilina O, Raiser O, Danilova A, Shevtsov V, Turzhanova A, Kalendar R 2021.
DNA profiling and assessment of genetic diversity of relict species Allium altaicum Pall. on the territory of Altai. PeerJ, 9:DOI:10.7717/peerj.10674

Turzhanova A, Khapilina O, Tumenbaeva A., Shevtsov V, Raiser O, Kalendar R 2020.
Genetic diversity of Alternaria species associated with black point in wheat grains. PeerJ, 8: e9097 DOI:10.7717/peerj.9097

Shevtsov V., Ismailova A., Aitimova U., Khapilina O.
Application of information systems and tools in bioinformatics // Scientific Journal of Astana IT University. - Vol 9. - March 2022. – Р. 14-21. DOI: 10.37943/AITU.2022.59.49.002

Raizer, O. B.; Khapilina, O. N.; Turzhanova, A. S.; Tagimanova, D. S.; Kalendar, R. N. 2020.
Polymorphism of genes of antioxidant system enzymes in cultivated wheat species and wild-growing relatives. Agrarian Bulletin of The on November 26, 2020 DOI:10.32417/1997-4868-2020-202-11-85-92

Райзер О. Б., Хапилина О. Н.
iPBS полиморфизм редких реликтовых и исчезающих видов Allium, произрастающих на территории Казахстанского Алтая // Аграрный вестник Урала. - 2020. - №. 09 (200). – С. 63-73. DOI: 10.32417/1997-4868-2020-200-9-63-73