Toxicology and Pharmacology Laboratory

Zhanar

Akhmetkarimova

Head of laboratory, Ph.D.

An expert in the realms of organic synthesis of biologically active compounds, polymer chemistry, nanomaterials, and mucoadhesion. Awarded the Talented Young Scientists Scholarship by the Republic of Kazakhstan in 2019 and named a scholar in the international Bolashak program “500 Scholars” in 2022. Currently holds memberships in the Royal Society of Chemists and the Academy of Pharmaceutical Sciences (2023, London, Manchester, United Kingdom). Completed internships at Xinjiang University in China (2012) and Reading University in the United Kingdom (2022-2023). Author of 14 original research papers featured in Scopus/Web of Science, 50 articles in nationally endorsed journals by the Committee for Control of Education and Science of the Ministry of Education and Science of the Republic of Kazakhstan, 1 patent issued by the Ministry of Justice of the Republic of Kazakhstan, 2 certificates of intellectual property, 2 monographs, and 1 educational guide.

ORCID ID – 0000-0002-9782-5521

Scopus ID – 55308246100

Research directions

  • Bioscreening;
  • Toxicology;
  • Biological models;
  • Regenerative pharmacology;
  • Drug delivery systems.

Core publications

Akhmetkarimova Z.S., Kudaibergen G.K., Kaukabaeva G.K., Abeldenov S.K., Rysbek A.B. (2023).
Thiol-Ene Click Synthesis of Alginate Hydrogels Loaded with Silver Nanoparticles and Cefepime. Eurasian Journal of Chemistry, 110(2), 59-68. CiteScore 2022 – 0.5, Q4. doi:10.31489/2959-0663/2-23-14.

Kudaibergen, G., Akhmetkarimova, Z., Yildirim, E., & Baidarbekov, M. (2023).
Thiol-ene clickable gelatin–hyaluronic acid cryogels. Journal of Materials Science, 1-11. CiteScore 2022 – 7.7, Q1. doi:10.1007/s10853-023-08693-z.

Sarsenova, M., Raimagambetov, Y., Issabekova, A., Karzhauov, M., Kudaibergen, G., Akhmetkarimova, Z., ... & Ogay, V. (2022).
Regeneration of Osteochondral Defects by Combined Delivery of Synovium-Derived Mesenchymal Stem Cells, TGF-β1 and BMP-4 in Heparin-Conjugated Fibrin Hydrogel. Polymers, 14(24), 5343. CiteScore 2022 – 6.6, Q1. doi:10.3390/polym14245343.

Toktarov T., Saginov B., Raimagambetov Y., Akhmetkarimova Z, Kudaibergen G.K., Kaukabaeva G.K., ...& Ogay, V. (2022).
Heparin-Conjugated Fibrin Hydrogel with Chondroinductive Growth Factors and Human Synovium-Derived Mesenchymal Stem Cells for the Treatment of Articular Cartilage Defects: Evaluation of Clinical Safety. International Journal of Biomedicine, 12(4), 539-547. CiteScore 2022 – 0.5, Q4. doi:10.21103/Article12(4) _OA3.

Akhmetkarimova, Z. & Temirgaziev, B. (2021).
Phytoecdysteroids: Chemical Structure and Biological Activity. Eurasian Journal of Applied Biotechnology, (2). doi: 10.11134/btp.2.2021.1