AR19679407 «Development of agrobiotechnologies for the introduction of a valuable medicinal and fodder plant, Rhaponticum carthamoides in Northern Kazakhstan»


Currently, natural plant resources provide a large amount of raw materials for industry, agriculture and medicine. However, every year this raw material becomes less and less. The reason is the depletion of the botanical composition of the grass stand, the disappearance of species valuable for food due to their instability to abiotic and biotic environmental factors. To solve this problem, it is necessary to conduct research on the introduction and expansion of the range of feed and medicinal crops that meet the needs of agriculture, medicine and the food industry. One of these crops is Rhaponticum carthamoides, containing various biologically active compounds (flavonoids, polysaccharides, saponins, cumanins). This species is of particular value as a producer of ultra-high quantities of ecdysteroids. Within the framework of this project, it is planned to conduct comprehensive research on the development of highly effective agrobiotechnological approaches to the propagation and conservation of the medicinal species Rhaponticum carthamoides for subsequent introduction and expansion of the range of forage crops.

Project goal

development of in vitro cultivation technologies and agrotechnical cultivation methods for the introduction of a valuable medicinal and fodder plant, Rhaponticum carthamoides in Northern Kazakhstan.

Expected results

  • Collection of initial plant material of R. carthamoídes will be carried out in places of natural growth
  • An in vitro collection of the valuable medicinal plant R. carthamoides will be created
  • A technology for in vitro propagation of the valuable medicinal plant R. carthamoídes will be developed for further introduction in the conditions of Northern Kazakhstan
  • An introduction nursery of wild specimens and regenerated plants of R. carthamoídes will be created for plantation cultivation in the steppe zone of Northern Kazakhstan
  • The potential for using R. carthamoídes as a forage crop when cultivated in the steppe zone of Northern Kazakhstan will be studied
  • The medicinal value of R. carthamoídes will be studied under different cultivation technologies in the steppe zone of Northern Kazakhstan.


Nagmetova G.Zh. Doctor of Philosophy (PhD) H-index – 1 ResearcherID: N-9822-2017 Scopus AuthorID: 57218566741 ORCID: 0000-0002-1848-6489

Research team members

Khapilina Oxana Nikolaevna, Candidate of Biological Sciences, Hirsch Index: 4; Researcher ID: J-4151-2017; ORCID: 0000-0002-7256-568X; Scopus Author ID: 57194829297

Aipova Rakhilya, Doctor of Philosophy (PhD), H index: 1; ORCID: 0000-0001-8318-6776 Scopus ID 57195069563;

Tagimanova Damelya Seitovna, master, Hirsch index: 1; Researcher ID: AGH-1325-2022; ORCID: 0000-0002-9020-4247; Scopus Author ID: 57194835810

Tumenbaeva Asem Ryskulbekovna, master, Hirsch index – 2; ORCID: 0000-0001-6360-1936; Scopus ID: 57216894029

Shevtsov Vladislav Aleksandrovich, master, Hirsch index – 3; ORCID: 0000-0001-6202-2123; Scopus ID: 57216896596

Turzhanova Ainur Serikovna, master, Hirsch index – 3; ORCID: 0000-0001-6205-9292; Scopus ID: 57216895766

Publications of the scientific supervisor and research group

  1. Nagmetova, G.; Berthold-Pluta, A.; Garbowska, M.; Kurmanbayev, A.; Stasiak-Różańska, L. Antibacterial Activity of Biocellulose with Oregano Essential Oil against Cronobacter Strains. Polymers 2020, 12, 1647.
  2. Nagmetova, G., Berdimuratova, K., Amirgazin, A., Shevtsov, V., Ismailova, A., Ramankulov, Y., Kurmanbayev, A. (2020). Draft Genome Sequence of a Potential Commercial Biocellulose Producer, Strain Komagataeibacter europaeus GH1. Microbiology Resource Announcements, 9(42). doi:10.1128/mra.00963-20
  3. Niyazbekova Zh.T., Nagmetova G.Zh., Kurmanbayev A.A. An overview of bacterial cellulose applications // Eurasian Journal of Applied Biotechnology. – 2018. – № 2. – P. 17-25.
  4. Nagmetova G.Zh., Kurmanbayev A.A. Isolation and identification of bacterial cellulose producers to obtain a biotechnological product promising for medicine and biotechnology // Eurasian journal of Applied Biotechnology. – 2019. – № 2. – Р. 116-122.
  5. Штамм Komagataeibacter sp.GH1, продуцирующий биоцеллюлозу, для использования в медицине и биотехнологии. Нагметова Г.Ж., Курманбаев А.А., Раманкулов Е.М. Пат. 5382 РК: C12N 1/20; заявитель и патентообладатель Нур-Султан, Нац. центр биотехнологии. №2020/0516.2; заявл. 02.06.2020; опубл.18.09.2020, Бюл. № 37 – 4 с.
  6. Тurzhanova, A., Khapilina, O.N., Tumenbayeva, A., Shevtsov, V., Raiser, O., Kalendar, R. Genetic diversity of Alternaria species associated with black point in wheat grains (2020) PeerJ, 2020 (3), e9097.
  7. Raiser O.B., Khapilina O.N. Culture in vitro of rare and endemic species of Allium (A. ledebourianum, A. altaicum), 2020. 2nd International Scientific Conference “Plants and Microbes: the Future of Biotechnology”. DOI: 10.28983/PLAMIC2020.204
  8. Khapilina O.N., Turzhanova A.S., Shevtsov V.A., Tumenbaeva A.R., Raiser O.B., Tagimanova D.S., Kalendar R.N. The study of genetic polymorphism of fungal pathogens using iPBS assays// Eurasian Journal of Applied Biotechnology. – 2020. – №1. – Р. 61-69. DOI: 10.11134/btp.1.2020.6
  9. Мaгзумoвa С.М. Регенерaция и рaзмнoжение лукa мелкoсетчaтoгo Allium microdictyon в услoвиях in vitro // Мaт.межд.нaучнoй кoнференции студентoв и мoлoдых ученых «Фaрaби Əлемі». – Aлмaты, 2020. – С.67.
  10. Рaйзер O.Б., Мaгзумoвa С.М. Oптимизaция культивирoвaния in vitro редких и эндемичных видoв лукa (A. ledebourianum, A. altaicum) // Мaт.межд.нaучнoй кoнференции студентoв и мoлoдых ученых «Фaрaби Əлемі». – Aлмaты, 2020. – С.77.
  11. Novakovskaya AP, Raizer OB, Danilova AN, Khapilina ON. In vitro cultivation of rare and endemic Allium sp. species // Eurasian Journal of Applied Biotechnology. – 2018. DOI: 10.11134/btp.2.2018.6
  12. Kalendar RN, Aizharkyn KS, Khapilina ON, Amenov AA, Tagimanova DS 2017. Plant diversity and transcriptional variability assessed by retrotransposon-based molecular markers. Vavilov Journal of Genetics and Breeding, 21(1): 128-134.
  13. Tagimanova DS, KhapilinaO., AmenovA., DanilovaA., Kalendar R. Genetic diversity of Rhodiola sp. in Altai as assessed by intron polymorphism markers// Eurasian Journal of Applied Biotechnology – 2017.-№2. – DOI: 10.11134/btp.2.2017.6
  14. Пaтент нa пoлезную мoдель №3755 «Спoсoб пoлучения рaстений лукa aлтaйскoгo в услoвиях in vitro» // Хaпилинa O.Н., Рaйзер O.Б., Кoтухoв Ю.A., Дaнилoвa A.Н., Нoвaкoвскaя A.П., Рaмaнкулoв Е.М. – Пaтентooблaдaтель: РГП «Нaциoнaльный центр биoтехнoлoгии» КН МOН РК. – oпубл.07.03.2019, Бюл. №10