Laboratory of Molecular Biotechnology




Specialist in the field of molecular genetics of microorganisms, genetic engineering, and DNA repair of pathogenic microorganisms. Researcher, Department of Clinical Microbiology, Hadassah Medical Center, Hebrew University of Jerusalem (Israel, 2008), Institut Gustave-Roussy DNA Repair Laboratory, National Center for Scientific Research, CNRS (France, 2013-2014). Author of more than 40 scientific publications, 4 Patents of the Republic of Kazakhstan.

ORCID ID – 0000-0002-6974-9138

Scopus ID – 56674705400

Research directions

  • Basic research in the field of DNA repair of human bacterial pathogens;
  • Preparation of recombinant tumor markers for the diagnosis and monitoring of oncological diseases;
  • Production of feed additives and probiotic preparations for use in agriculture.

Innovative developments

  • Collection of cultures of microorganisms with probiotic properties have been created;
  • The biochemical activity of Mycobacterium tuberculosis and Helicobacter pylori DNA repair enzymes has been characterized;
  • The production technology of the «Phytase» feed additive has been developed.

Core publications

Turgimbayeva, A., Abeldenov, S., Sarina, N., Khassenov, B., Eskendirova, S.
Obtaining Specific Hybridomas for Ki-67 Protein Immunodetection // Indonesian Biomedical Journal

Rysbek A., Ramankulov Ye., Kurmanbayev A., Richert A., Abeldenov S.
Comparative characterization and identification of poly-3-hydroxybutyrate producing bacteria with subsequent optimization of polymer yield // Polymers. - 2022.

Turgimbayeva, A., Zein, U., Zharkov, D., Ramankulov, Ye., Saparbaev, M., Abeldenov, S.
Cloning and characterization of the major AP endonuclease from Staphylococcus aureus // DNA Repair. - 2022

Азнабаева Р.Б., Тургимбаева А.М., Зейн Ұ.Ө., Абельденов С.К.
Пептидные последовательности для белок-белковых взаимодействий скользящего зажима // Вестник Карагандинского университета. – 2022.

Kabylbayeva A., Zharylgassynova K., Abilova A., Amanzholova M., Abeldenov S.
CRISPR/Cas12a-based diagnostics for COVID-19 // Eurasian Journal of Applied Biotechnology. – 2021

Аманжолова, М.Ж., Шайзадинова А.М., Абельденов С.К.
Экспрессия и очистка рекомбинантной ДНК эндонуклеазы CRISPR/Cas системы // Вестник Карагандинского университета. – 2022.